Agenda | Liver Connect

AGENDA

THURSDAY, March 20, 2025

7:00 AM – 4:30 PM

Registration

Pediatric Connect I Breakout Session

Co-chairs/moderators: Carina Kugelmas, MD; and Miriam Vos, MD, MSPH

8:00 – 8:10 AM

Welcome

Miriam Vos, MD, MSPH

Part I: Hepatology Potpourri

Moderators: Miriam Vos, MD, MSPH and Rohit Kohli, MBBS, MS

8:10 – 8:30 AM

Lipodystrophy: Finding the Needle in the Haystack

Rebecca Brown, MD, MHSc

8:30 AM – 8:45 AM

Modern Approaches in Mitochondrial Liver Disease

Ronald Sokol, MD

8:45 – 9:15 AM

Cases for Contemplation: Panel Discussion-Case Based

Rebecca Brown, MD, MHSc; Ryan Fischer, MD; Samar Ibrahim, MB, ChB; Ronald Sokol, MD; and Jeffrey Teckman, MD

Part II: Hepatology Potpourri

Moderators: Rima Fawaz, MD and Ronald Sokol, MD

9:15 – 9:40 AM

Keynote: Wilson's Emerging Challenges

Michael Schilsky, MD

9:40 – 10:00 AM

Cases for Contemplation: Panel Discussion-Case Based

Regino Gonzalez-Peralta, MD; Alyssa A. Kriegermeier, MD; Anna Peters, MD, PhD; and Michael Schilsky, MD

10:00 – 10:15 AM

Break

Part III: Pediatric Cholestatic Disease

Moderators: Regino Gonzalez-Peralta, MD and Nitika Gupta, MD

10:15 – 10:30 AM

Nutritional Management: New Guidelines on Managing Fat Soluble Vitamin Deficiency

Amal Aqul, MD

10:30 – 10:45 AM

VOUS or Not? Clinical use of Genetic Panels for Cholestatic Disease

Kathleen Loomes, MD

10:45 – 11:00 AM

Making the Case for Pruritus Treatment: Case-based Examples of Therapeutic Decision Making

Mercedes Martinez, MD

11:00 – 11:30 AM

Cases for Contemplation: Panel Discussion-Case Based

Empowering APPs: Fostering Collaboration and Education for 2025 and Beyond

Amal Aqul, MD; Jamie Chu, MD; Karan Emerick, MD; Kathleen Loomes, MD; and Mercedes Martinez, MD

11:30 – 11:45 AM

Pediatric Connect Closing Remarks

Carina Kugelmas, MD

11:45 AM – 12:15 PM

Break

12:15 – 1:00 PM

Lunch Industry-Sponsored Event

1:00 – 1:15 PM

Break

1:15 – 1:30 PM

Welcome and Introductions

Zobair Younossi, MD, MPH

1:30 – 2:00 PM

Keynote: Finding Happiness in Your Career

Patrick Kamath, MD

Session I: Autoimmune Cholestatic Liver Disease

Advances in PBC, PSC, and Autoimmune Hepatitis

Co-chairs: Kris Kowdley, MD, and Raj Vuppalanchi, MD

2:00 – 2:20 PM

Current Landscape in PBC Diagnosis and Treatment

Kris Kowdley, MD

2:20 – 2:35 PM

Debate: Second-Line Therapy Options in PBC

Moderator: John Vierling, MD

Aparna Goel, MD and Craig Lammert, MD

2:35 – 2:55 PM

Assessment and Therapy of Symptoms in PBC

Mark G. Swain, MD, MSc

2:55 – 3:15 PM

Q&A/Panel Discussion

3:15 – 3:30 PM

Break

3:30 – 3:45 PM

Spotlight on Drug-Induced Autoimmune Hepatitis and Immune-Mediated Liver Injury

Lily Dara, MD

3:45 – 4:00 PM

Overview of PSC: Mechanisms and Emerging Therapies

Christopher Bowlus, MD

4:00 – 4:15 PM

Updates in Autoimmune Hepatitis

Craig Lammert, MD

4:15 – 4:30 PM

Q&A/Panel Discussion

4:30 – 4:45 PM

Break

Session II: Alcohol-Associated Liver Disease

New Horizons in Treating Alcohol-Associated Hepatitis: Therapies, Strategies, and Debates

Co-chairs: Steven Flamm, MD, Mack Mitchell, MD, and Ashwani Singal, MD, MS

4:45 – 5:05 PM

Recognition and Treatment of Compensated ALD/MetALD

Ashwani Singal, MD, MS

5:05 – 5:25 PM

Treatment of AUD in Patients with ALD

To be announced

5:25 – 5:45 PM

Early Liver Transplant in ALD: Efficacy, Ethical Concerns and Disparities Issues on Organ Allocation

To be announced

5:45 – 6:00 PM

Q&A / Panel Discussion

6:15 – 7:00 PM

Dinner Industry-Sponsored Event

FRIDAY, March 21, 2025

7:00 – 4:45 PM

Registration

7:45 – 8:30 AM

Breakfast Industry-Sponsored Event

8:30 – 9:00 AM

Break/Visit Exhibits

Session III: MASH/MASLD

Innovations in MASLD Management: From NITs to Multidisciplinary Approaches and Extrahepatic Comorbidities
Co-chairs: Alina Allen, MD, and Zobair Younossi, MD, MPH

9:00 – 9:05 AM

Welcome Back

Zobair Younossi, MD, MPH

9:05 AM – 9:35 AM

Keynote: The Evolution of MASH and Fibrosis Over Decades

Scott Friedman, MD

9:35 AM – 9:50 AM

Practical Use of NITs
Alina Allen, MD

9:50 – 10:15 AM

Expert Panel Discussion: The Role of NITs
Moderator: Naim Alkhouri, MD

Panelists: Alina Allen, MD; Mandeep Bajaj, MD; and Scott Friedman, MD

10:15 – 10:30 AM

Break / Visit Exhibits

10:30 – 10:45 AM

Current Management: Obesity and Type-2 Diabetes in MASLD

Christos Mantzoros, MD

10:45 – 11:00 AM

MASH Targeted Therapy-Current and Future

Manal Abdelmalek, MD, MPH

11:00 – 11:25 AM

Expert Panel Discussion: Management of MASLD

Moderator: Zobair Younossi, MD, MPH

Panelists: Manal Abdelmalek, MD, MPH; Mandeep Bajaj, MD; Scott Isaacs, MD; and Christos Mantzoros, MD, DSc, PhD

11:25 – 11:40 AM

Extrahepatic Diseases Associated with MASLD (CVD, CKD, Cancer and Sarcopenia)

Naim Alkhouri, MD

11:40 – 11:55 AM

Role of Multi-disciplinary Team in Management of MASLD

Mazen Noureddin, MD, MHSc

11:55 AM – 12:20 PM

Expert Panel Discussion: Models of Care

Moderator: Sonal Kumar, MD MPH

Panelists: Mazen Noureddin, MD, MHSc; Scott Isaacs, MD; Christos Mantzoros, MD, DSc, PhD

12:20 – 12:30 PM

Session Wrap-up

Zobair Younossi, MD, MPH

12:30 – 1:00 PM

Lunch Break

1:00 – 1:45 PM

Industry-Sponsored Event

1:45 – 2:00 PM

Break

Session IV: Cirrhosis

Advancing Care in Cirrhosis: A Case-Based Approach to Alpha-1 Antitrypsin Deficiency, Portal Hypertension, and Acute on Chronic Liver Failure
Co-chairs: Marcelo Kugelmas, MD and Sammy Saab, MD, MPH

2:00 – 2:10 PM

Session Introduction

Marcelo Kugelmas, MD

2:10 – 2:40 PM

Case 1

Ranjeeta Bahirwani, MD; Arun Jesudian, MD; Paul Kwo, MD;
Mina Rakoski, MD; and Sammy Saab, MD, MPH

2:40 – 3:10 PM

Case 2

Marcelo Kugelmas, MD; Carmen Landaverde, MD; Akshay Shetty, MD; and Robert Wong, MD, MS

3:10 – 3:40 PM

Case 3

David S. Goldberg, MD, MSCE; Sammy Saab, MD, MPH;
Monica Tincopa, MD, MS; Hirsh D. Trivedi, MD, MS; and Kali Zhou, MD

3:40 – 3:45 PM

Case Wrap-up

3:45 – 4:00 PM

Break

4:00 – 4:05 PM

Keynote Introduction

Marcelo Kugelmas, MD

4:05 – 4:35 PM

Keynote: Management of Portal Vein Thrombosis

Steven Flamm, MD

4:35 – 4:50 PM

Q&A / Panel Discussion

4:50 – 5:00 PM

Wrap-up

Marcelo Kugelmas, MD

5:00 – 5:15 PM

Break

5:15 – 6:00 PM

Dinner Industry-Sponsored Event

6:00 PM – 7:00 PM I Breakout Session

Pediatric MASLD Roundtable Discussion

Co-chairs: Carina Kugelmas, MD, and Miriam Vos, MD, MSPH

Stavra Xanthakos, MD, MS, Marialena Mouzaki, MD, MSc, Rohit Kohli, MBBS, MS, Jennifer Panganiban, MD, and Jeffery Schwimmer, MD

7:00 PM – 8:30 PM

Conference Reception & Poster Display

SATURDAY, March 22, 2025

7:45 – 8:30 AM

Breakfast Industry-Sponsored Event

8:30 – 9:00 AM
Break/Visit Exhibits

9:00 – 9:05 AM

Welcome Back

Ira Jacobson, MD

Session V: Viral Hepatitis
Co-chairs: Ira Jacobson, MD, and Paul Martin, MD

9:00 – 9:20 AM

Exploring the Nuances of Hepatitis Vaccination: Are We Doing Enough?

Paul Kwo, MD

9:20 – 9:40 AM

Navigating Expanding Guidelines for Hepatitis B: Which Are Right for Your Patients?

Douglas Dieterich, MD

9:40 – 10:00 AM

Emerging Treatments for Hepatitis B on the Horizon

Ira Jacobson, MD

10:00 – 10:20 AM

Hepatitis D: Strategies for Treatment and Management

Tatyana Kushner, MD, MSCE

10:20 – 10:40 AM

Case Discussion

Moderated by Paul Martin, MD

10:40 – 11:00 AM

Q&A/Panel Discussion

11:00 – 11:15 AM

Break/Visit Exhibits

Session VI: HCC

Advances in Liver Cancer Therapy: IR, Systemic Treatments, and Neoadjuvant Approaches

Co-chairs: Aijaz Ahmed, MD, Laura Kulik, MD and Robert Wong, MD, MS

11:15 – 11:30 AM

Interventional Radiology (IR) Local Regional

Siddharth A. Padia, MD

11:30 – 11:40 AM

How Do Systemic Therapies and LRT Fit into the Treatment of Unresectable HCC?

Laura Kulik, MD

11:40 – 11:55 AM

Evolving Role of Neoadjuvant Systemic Therapy for Transplant

Parissa Tabrizian, MD

11:55 AM – 12:15 PM

Q&A/Panel Discussion

12:15 – 12:30 PM

Closing Remarks

12:30 – 1:15 PM

Lunch

1:15 – 1:30 PM

Transition Break

1:30 – 3:00 PM I Breakout Session

APP Session

Marcelo Kugelmas, MD and Aijaz Ahmed, MD

1:30 – 3:30 PM I Breakout Session

Fellows Summit

Kimberly Brown, MD and Steven Flamm, MD